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Genetic deletion of galectin-3 enhances neuroinflammation, affects microglial activation and contributes to sub-chronic injury in experimental neonatal focal stroke

The pathophysiology of neonatal stroke and adult stroke are distinct in many aspects, including the inflammatory response. We previously showed endogenously protective functions of microglial cells in acute neonatal stroke. We asked if galectin-3 (Gal3), a pleotropic molecule that mediates interacti...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Chip, Sophorn, Fernández-López, David, Li, Fan, Faustino, Joel, Derugin, Nikita, Vexler, Zinaida S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909718/
https://ncbi.nlm.nih.gov/pubmed/27836669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2016.11.005
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