Cloning and high-level expression of monomeric human superoxide dismutase 1 (SOD1) and its interaction with pyrimidine analogs

Superoxide dismutase 1 (SOD1) is known to be involved in the pathogenesis of Amyotrophic Lateral Sclerosis (ALS) and is therefore considered to be an important ALS drug target. Identifying potential drug leads that bind to SOD1 and characterizing their interactions by nuclear magnetic resonance (NMR...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: LeVatte, Marcia, Lipfert, Matthias, Roy, Dipankar, Kovalenko, Andriy, Wishart, David Scott
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909654/
https://ncbi.nlm.nih.gov/pubmed/33635895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247684
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