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Cloning and high-level expression of monomeric human superoxide dismutase 1 (SOD1) and its interaction with pyrimidine analogs

Superoxide dismutase 1 (SOD1) is known to be involved in the pathogenesis of Amyotrophic Lateral Sclerosis (ALS) and is therefore considered to be an important ALS drug target. Identifying potential drug leads that bind to SOD1 and characterizing their interactions by nuclear magnetic resonance (NMR...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: LeVatte, Marcia, Lipfert, Matthias, Roy, Dipankar, Kovalenko, Andriy, Wishart, David Scott
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909654/
https://ncbi.nlm.nih.gov/pubmed/33635895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247684
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