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Biological and Clinical Consequences of Integrin Binding via a Rogue RGD Motif in the SARS CoV-2 Spike Protein

Although ACE2 (angiotensin converting enzyme 2) is considered the primary receptor for CoV-2 cell entry, recent reports suggest that alternative pathways may contribute. This paper considers the hypothesis that viral binding to cell-surface integrins may contribute to the high infectivity and widesp...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Makowski, Lee, Olson-Sidford, William, W. Weisel, John
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909284/
https://ncbi.nlm.nih.gov/pubmed/33498225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13020146
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