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The impact of baseline brain metastases on clinical benefits and progression patterns after first-line crizotinib in anaplastic lymphoma kinase-rearranged non-small cell lung cancer

Baseline brain metastasis (BBM) commonly occurs in anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer. Crizotinib prolongs the survival of patients with ALK rearrangement but lacks significant effect on brain metastasis. It remains unclear whether BBM and local therapy affect the...

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Bibliografiske detaljer
Udgivet i:Medicine (Baltimore)
Main Authors: Chen, Yuqi, Cai, Chengzhi, Li, Yanying
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909142/
https://ncbi.nlm.nih.gov/pubmed/33663095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000024784
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