Association of Risk-Reducing Salpingo-Oophorectomy With Breast Cancer Risk in Women With BRCA1 and BRCA2 Pathogenic Variants

IMPORTANCE: Women with pathogenic variants in BRCA1 and BRCA2 are at high risk of developing breast and ovarian cancers. They usually undergo intensive cancer surveillance and may also consider surgical interventions, such as risk-reducing mastectomy or risk-reducing salpingo-oophorectomy (RRSO). Ri...

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Dettagli Bibliografici
Pubblicato in:JAMA Oncol
Autori principali: Choi, Yun-Hee, Terry, Mary Beth, Daly, Mary B., MacInnis, Robert J., Hopper, John L., Colonna, Sarah, Buys, Saundra S., Andrulis, Irene L., John, Esther M., Kurian, Allison W., Briollais, Laurent
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2021
Soggetti:
Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907985/
https://ncbi.nlm.nih.gov/pubmed/33630024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2020.7995
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