Low Distribution of TIM-3(+) Cytotoxic Tumor-Infiltrating Lymphocytes Predicts Poor Outcomes in Gastrointestinal Stromal Tumors

There are multiple tumor-infiltrating lymphocytes (TILs) and relevant immune checkpoints existing in gastrointestinal stromal tumor (GIST), which provides opportunities and rationales for developing effective immunotherapies. Recent studies have suggested that checkpoint TIM-3/Gal-9 plays a pivotal...

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Pubblicato in:J Immunol Res
Autori principali: Zhuang, Chun, Ni, Bo, Zhang, Zi-Zhen, Zhao, Wen-Yi, Tu, Lin, Ma, Xin-Li, Yang, Lin-Xi, Cao, Hui, Wang, Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907748/
https://ncbi.nlm.nih.gov/pubmed/33681387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6647292
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