Increased Mesenchymal Stem Cell Functionalization in Three-Dimensional Manufacturing Settings for Enhanced Therapeutic Applications

Mesenchymal stem/stromal cell (MSC) exist within their in vivo niches as part of heterogeneous cell populations, exhibiting variable stemness potential and supportive functionalities. Conventional extensive 2D in vitro MSC expansion, aimed at obtaining clinically relevant therapeutic cell numbers, r...

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Bibliographic Details
Published in:Front Bioeng Biotechnol
Main Authors: Kouroupis, Dimitrios, Correa, Diego
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Bioengineering and Biotechnology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907607/
https://ncbi.nlm.nih.gov/pubmed/33644016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.621748
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