Novel Göttingen Miniswine Model of Heart Failure With Preserved Ejection Fraction Integrating Multiple Comorbidities

A lack of preclinical large animal models of heart failure with preserved ejection fraction (HFpEF) that recapitulate this comorbid-laden syndrome has led to the inability to tease out mechanistic insights and to test novel therapeutic strategies. This study developed a large animal model that integ...

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Pubblicato in:JACC Basic Transl Sci
Autori principali: Sharp, Thomas E., Scarborough, Amy L., Li, Zhen, Polhemus, David J., Hidalgo, Hunter A., Schumacher, Jeffery D., Matsuura, Timothy R., Jenkins, J. Stephen, Kelly, Daniel P., Goodchild, Traci T., Lefer, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
Soggetti:
Novel Translational Models
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907541/
https://ncbi.nlm.nih.gov/pubmed/33665515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2020.11.012
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