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Dispersion as a waste-clearance mechanism in flow through penetrating perivascular spaces in the brain

Accumulation of metabolic wastes in the brain is correlated with several neurodegenerative disorders, including Alzheimer’s disease. Waste transport and clearance occur via dispersion, the combined effect of diffusion and advection by flow of fluid. We examine the relative contributions of diffusion...

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Vydáno v:Sci Rep
Hlavní autoři: Troyetsky, Daniel E., Tithof, Jeffrey, Thomas, John H., Kelley, Douglas H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907360/
https://ncbi.nlm.nih.gov/pubmed/33633194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83951-1
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