Adipose-derived mesenchymal stem cells differentiate into heterogeneous cancer-associated fibroblasts in a stroma-rich xenograft model

Cancer-associated fibroblasts (CAFs) are the key components of the densely proliferated stroma in pancreatic ductal adenocarcinoma (PDAC) and contribute to tumor progression and drug resistance. CAFs comprise heterogeneous subpopulations playing unique and vital roles. However, the commonly used mou...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Miyazaki, Yoshihiro, Oda, Tatsuya, Inagaki, Yuki, Kushige, Hiroko, Saito, Yutaka, Mori, Nobuhito, Takayama, Yuzo, Kumagai, Yutaro, Mitsuyama, Toutai, Kida, Yasuyuki S.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907195/
https://ncbi.nlm.nih.gov/pubmed/33633222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84058-3
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