BACH2 Enforces the Transcriptional and Epigenetic Programs of Stem-Like CD8(+) T cells

During chronic infection and cancer, a self-renewing CD8(+) T cell subset maintains long-term immunity and is critical to the effectiveness of immunotherapy. These stem-like CD8(+) T cells diverge from other CD8(+) subsets early after chronic viral infection. However, pathways guarding stem-like CD8...

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Publicado no:Nat Immunol
Main Authors: Yao, Chen, Lou, Guohua, Sun, Hong-Wei, Zhu, Ziang, Sun, Yi, Chen, Zeyu, Chauss, Daniel, Moseman, E. Ashley, Cheng, Jun, D’Antonio, Marc A., Shi, Wangke, Shi, Junwei, Kometani, Kohei, Kurosaki, Tomohiro, Wherry, E. John, Afzali, Behdad, Gattinoni, Luca, Zhu, Yuwen, McGavern, Dorian B., O’Shea, John J., Schwartzberg, Pamela L., Wu, Tuoqi
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906956/
https://ncbi.nlm.nih.gov/pubmed/33574619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-021-00868-7
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