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Emerging Roles of SIRT6 in Human Diseases and Its Modulators

The biological functions of SIRT6 (e.g. deacetylation, defatty-acylation and mono-ADP-ribosylation) play a pivotal role in regulating lifespan and several fundamental processes controlling aging such as DNA repair, gene expression, and telomeric maintenance. Over the past decades, aberration of SIRT...

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Bibliographic Details
Published in:Med Res Rev
Main Authors: Liu, Gang, Chen, Haiying, Liu, Hua, Zhang, Wenbo, Zhou, Jia
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906922/
https://ncbi.nlm.nih.gov/pubmed/33325563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.21753
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