Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine (CoronaVac) in healthy adults aged 60 years and older: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial

BACKGROUND: A vaccine against COVID-19 is urgently needed for older adults, in whom morbidity and mortality due to the disease are increased. We aimed to assess the safety, tolerability, and immunogenicity of a candidate COVID-19 vaccine, CoronaVac, containing inactivated SARS-CoV-2, in adults aged...

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Udgivet i:Lancet Infect Dis
Main Authors: Wu, Zhiwei, Hu, Yaling, Xu, Miao, Chen, Zhen, Yang, Wanqi, Jiang, Zhiwei, Li, Minjie, Jin, Hui, Cui, Guoliang, Chen, Panpan, Wang, Lei, Zhao, Guoqing, Ding, Yuzhu, Zhao, Yuliang, Yin, Weidong
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Ltd. 2021
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906628/
https://ncbi.nlm.nih.gov/pubmed/33548194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(20)30987-7
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