Guizhi-Shaoyao-Zhimu decoction attenuates bone erosion in rats that have collagen-induced arthritis via modulating NF‐κB signalling to suppress osteoclastogenesis

CONTEXT: Guizhi-Shaoyao-Zhimu decoction (GSZD) is commonly used to treat rheumatoid arthritis (RA), but its mechanism is unclear. OBJECTIVE: To investigate the effect of GSZD on bone erosion in type II collagen (CII)-induced arthritis (CIA) in rats and to identify the underlying mechanism. MATERIALS...

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Bibliographic Details
Published in:Pharm Biol
Main Authors: Wei, Shu-jun, Zhang, Qing, Xiang, Yong-jing, Peng, Lan-yu, Peng, Wei, Ren, Qiang, Gao, Yong-xiang
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2021
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906619/
https://ncbi.nlm.nih.gov/pubmed/33626293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2021.1876100
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