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From heterogeneous healthcare data to disease-specific biomarker networks: A hierarchical Bayesian network approach

In this work, we introduce an entirely data-driven and automated approach to reveal disease-associated biomarker and risk factor networks from heterogeneous and high-dimensional healthcare data. Our workflow is based on Bayesian networks, which are a popular tool for analyzing the interplay of bioma...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Becker, Ann-Kristin, Dörr, Marcus, Felix, Stephan B., Frost, Fabian, Grabe, Hans J., Lerch, Markus M., Nauck, Matthias, Völker, Uwe, Völzke, Henry, Kaderali, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906470/
https://ncbi.nlm.nih.gov/pubmed/33577591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008735
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