Tumor-associated macrophages promote pancreatic ductal adenocarcinoma progression by inducing epithelial-to-mesenchymal transition

In this study, we investigated the role of tumor-associated macrophages (TAMs) in the progression of pancreatic ductal adenocarcinoma (PDAC). PDAC patients with higher levels of CD68(+) TAMs exhibited shorter overall survival. In Transwell assays, PDAC cells incubated with TAMs or conditioned media...

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Xiong, Cheng, Zhu, Youwei, Xue, Meilin, Jiang, Yongsheng, Zhong, Yiming, Jiang, Lingxi, Shi, Minmin, Chen, Hao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2021
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906203/
https://ncbi.nlm.nih.gov/pubmed/33428605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202264
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