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Interplay and roles of oxidative stress, toll-like receptor 4 and Nrf2 in trichloroethene-mediated autoimmunity

Previous studies in MRL +/+ mice suggest involvement of oxidative stress (OS) in trichloroethene (TCE)-mediated autoimmunity. However, molecular mechanisms underlying the autoimmunity remain to be fully elucidated. Even though toll-like receptors (TLRs) and Nuclear factor (erythroid-derived 2)-like2...

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Pubblicato in:Toxicol Appl Pharmacol
Autori principali: Wang, Gangduo, Wang, Hui, Banerjee, Nivedita, Khan, M. Firoze
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906116/
https://ncbi.nlm.nih.gov/pubmed/33007382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2020.115258
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