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Comprehensive analysis of tumour mutational burden and its clinical significance in prostate cancer

BACKGROUND: The tumorigenesis of prostate cancer involves genetic mutations. Tumour mutational burden (TMB) is an emerging biomarker for predicting the efficacy of immunotherapy. RESULTS: Single-nucleotide polymorphisms were the most common variant type, and C>T transversion was the most commonly...

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Detalhes bibliográficos
Publicado no:BMC Urol
Main Authors: Wang, Lijuan, Pan, Shucheng, Zhu, Binbin, Yu, Zhenliang, Wang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905899/
https://ncbi.nlm.nih.gov/pubmed/33632199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12894-021-00795-7
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