GPR4 signaling is essential for the promotion of acid-mediated angiogenic capacity of endothelial progenitor cells by activating STAT3/VEGFA pathway in patients with coronary artery disease

BACKGROUND: Patients with coronary artery disease (CAD) are characterized by a decline in vascular regeneration, which is related to the dysfunction of endothelial progenitor cells (EPCs). G-protein-coupled receptor 4 (GPR4) is a proton-sensing G-protein-coupled receptor (GPCR) that contributes to n...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Ouyang, Shun, Li, Yan, Wu, Xing, Wang, Yan, Liu, Fanmao, Zhang, Jianning, Qiu, Yumin, Zhou, Zhe, Wang, Zhichao, Xia, Wenhao, Lin, Xiufang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905863/
https://ncbi.nlm.nih.gov/pubmed/33632325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02221-z
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