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G-quadruplexes: a promising target for cancer therapy

DNA and RNA can fold into a variety of alternative conformations. In recent years, a particular nucleic acid structure was discussed to play a role in malignant transformation and cancer development. This structure is called a G-quadruplex (G4). G4 structure formation can drive genome instability by...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Kosiol, Nils, Juranek, Stefan, Brossart, Peter, Heine, Annkristin, Paeschke, Katrin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905668/
https://ncbi.nlm.nih.gov/pubmed/33632214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-021-01328-4
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