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Penalized partial least squares for pleiotropy

BACKGROUND: The increasing number of genome-wide association studies (GWAS) has revealed several loci that are associated to multiple distinct phenotypes, suggesting the existence of pleiotropic effects. Highlighting these cross-phenotype genetic associations could help to identify and understand co...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Broc, Camilo, Truong, Therese, Liquet, Benoit
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905667/
https://ncbi.nlm.nih.gov/pubmed/33627076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-03968-1
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