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Abelson kinase’s intrinsically disordered region plays essential roles in protein function and protein stability
BACKGROUND: The non-receptor tyrosine kinase Abelson (Abl) is a key player in oncogenesis, with kinase inhibitors serving as paradigms of targeted therapy. Abl also is a critical regulator of normal development, playing conserved roles in regulating cell behavior, brain development and morphogenesis...
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| 出版年: | Cell Commun Signal |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7905622/ https://ncbi.nlm.nih.gov/pubmed/33627133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00703-w |
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