Age-Related Gene Alteration in Naïve and Memory T cells Using Precise Age-Tracking Model

In aged individuals, age-related changes in immune cells, especially T cell deficiency, are associated with an increased incidence of infection, tumor, and autoimmune disease, as well as an impaired response to vaccination. However, the features of gene expression levels in aged T cells are still un...

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Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Yang, Xiaofeng, Wang, Xin, Lei, Lei, Sun, Lina, Jiao, Anjun, Zhu, Kun, Xie, Tao, Liu, Haiyan, Zhang, Xingzhe, Su, Yanhong, Zhang, Cangang, Shi, Lin, Zhang, Dan, Zheng, Huiqiang, Zhang, Jiahui, Liu, Xiaobin, Zhou, Xiaobo, Sun, Chenming, Zhang, Baojun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905051/
https://ncbi.nlm.nih.gov/pubmed/33644036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.624380
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