βA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity

βA3/A1-crystallin, a lens protein that is also expressed in astrocytes, is produced as βA3 and βA1-crystallin isoforms by leaky ribosomal scanning. In a previous human proteome high-throughput array, we found that βA3/A1-crystallin interacts with protein tyrosine phosphatase 1B (PTP1B), a key regula...

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Publicado no:Commun Biol
Main Authors: Ghosh, Sayan, Liu, Haitao, Yazdankhah, Meysam, Stepicheva, Nadezda, Shang, Peng, Vaidya, Tanuja, Hose, Stacey, Gupta, Urvi, Calderon, Michael Joseph, Hu, Ming-Wen, Nair, Archana Padmanabhan, Weiss, Joseph, Fitting, Christopher S., Bhutto, Imran A., Gadde, Santosh Gopi Krishna, Naik, Naveen Kumar, Jaydev, Chaitra, Lutty, Gerard A., Handa, James T., Jayagopal, Ashwath, Qian, Jiang, Sahel, José-Alain, Rajasundaram, Dhivyaa, Sergeev, Yuri, Zigler, J. Samuel, Sethu, Swaminathan, Watkins, Simon, Ghosh, Arkasubhra, Sinha, Debasish
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904954/
https://ncbi.nlm.nih.gov/pubmed/33627831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01763-5
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