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Optogenetic current in myofibroblasts acutely alters electrophysiology and conduction of co-cultured cardiomyocytes

Interactions between cardiac myofibroblasts and myocytes may slow conduction and generate spontaneous beating in fibrosis, increasing the chance of life-threatening arrhythmia. While co-culture studies have shown that myofibroblasts can affect cardiomyocyte electrophysiology in vitro, the extent of ...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Kostecki, Geran M., Shi, Yu, Chen, Christopher S., Reich, Daniel H., Entcheva, Emilia, Tung, Leslie
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904933/
https://ncbi.nlm.nih.gov/pubmed/33627695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83398-4
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