Sodium 4-Phenylbutyrate Protects Hypoxic-Ischemic Brain Injury via Attenuating Endoplasmic Reticulum Stress in Neonatal Rats

Neonatal hypoxic-ischemic (HI) brain injury is associated with long-term neurological disorders, and protective strategies are presently scarce. Sodium 4-phenylbutyrate (4-PBA) reportedly acts as a chemical chaperone that alleviates endoplasmic reticulum (ER) stress, which plays a critical role in n...

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Bibliographic Details
Published in:Front Behav Neurosci
Main Authors: Wu, Ziyi, Niu, Jiayuan, Xue, Hang, Wang, Shuo, Zhao, Ping
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904702/
https://ncbi.nlm.nih.gov/pubmed/33643009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2021.632143
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