Improving the Methanol Tolerance of an Escherichia coli Methylotroph via Adaptive Laboratory Evolution Enhances Synthetic Methanol Utilization

There is great interest in developing synthetic methylotrophs that harbor methane and methanol utilization pathways in heterologous hosts such as Escherichia coli for industrial bioconversion of one-carbon compounds. While there are recent reports that describe the successful engineering of syntheti...

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Bibliographische Detailangaben
Veröffentlicht in:Front Microbiol
Hauptverfasser: Bennett, R. Kyle, Gregory, Gwendolyn J., Gonzalez, Jacqueline E., Har, Jie Ren Gerald, Antoniewicz, Maciek R., Papoutsakis, Eleftherios T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904680/
https://ncbi.nlm.nih.gov/pubmed/33643274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.638426
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