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“Double-punch” strategy for delivery of viral immunotherapy with prolonged tumor retention and enhanced transfection efficacy

Viral immunotherapy has shown clinical efficacy in treating cancers (e.g., melanoma). Given that viral immunotherapy commonly uses intratumoral injection, prolonging the duration of therapeutic virus at the tumor site can further enhance the antitumor efficacy and reduce potential off-target effects...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Wang, Juan, Guo, Chunqing, Wang, Xiang-Yang, Yang, Hu
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904666/
https://ncbi.nlm.nih.gov/pubmed/33278479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.11.043
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