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Peptide Conjugation Enhances the Cellular Co-localization, but not Endosomal Escape, of Modular Poly(Acrylamide-co-Methacrylic Acid) Nanogels

Nanoparticles must recognize, adhere to, and/or traverse multiple barriers in sequence to achieve cytosolic drug delivery. New nanoparticles often exhibit a unique ability to cross a single barrier (i.e. the vasculature, cell membrane, or endosomal compartment), but fail to deliver an adequate dose...

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Bibliographische Detailangaben
Veröffentlicht in:J Control Release
Hauptverfasser: Clegg, John R., Sun, Jessie A., Gu, Joann, Venkataraman, Abhijeet K., Peppas, Nicholas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904656/
https://ncbi.nlm.nih.gov/pubmed/33127451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.10.045
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