Mitochondrial OPA1 cleavage is reversibly activated by differentiation of H9c2 cardiomyoblasts.

Optic atrophy-1 (OPA1) is a dynamin-like GTPase localized to the mitochondrial inner membrane, playing key roles in inner membrane fusion and cristae maintenance. OPA1 is regulated by the mitochondrial transmembrane potential (Δψ(m)): when Δψ(m) is intact, long OPA1 isoforms (L-OPA1) carry out inner...

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Veröffentlicht in:Mitochondrion
Hauptverfasser: Garcia, Iraselia, Calderon, Fredy, De la Torre, Patrick, St. Vallier, Shaynah, Rodriguez, Cristobal, Agarwala, Divya, Keniry, Megan, Innis-Whitehouse, Wendy, Gilkerson, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904612/
https://ncbi.nlm.nih.gov/pubmed/33383158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2020.12.007
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