Plasma cells shape the mesenchymal identity of ovarian cancers through transfer of exosome-derived microRNAs

Ovarian cancer represents a highly lethal disease that poses a substantial burden for females, with four main molecular subtypes carrying distinct clinical outcomes. Here, we demonstrated that plasma cells, a subset of antibody-producing B cells, were enriched in the mesenchymal subtype of high-grad...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Adv
Hauptverfasser: Yang, Zhengnan, Wang, Wei, Zhao, Linjie, Wang, Xin, Gimple, Ryan C., Xu, Lian, Wang, Yuan, Rich, Jeremy N., Zhou, Shengtao
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2021
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904265/
https://ncbi.nlm.nih.gov/pubmed/33627414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb0737
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