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Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1

Breast cancer is the leading cause of cancer-related deaths in the United States. The majority of deaths (90%) in breast cancer patients is caused by invasion and metastasis–two features related to the epithelial-to-mesenchymal transition (EMT). Twist1 is a key transcription factor that promotes the...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nafie, Ebtesam, Lolarga, Jade, Lam, Brandon, Guo, Jonathan, Abdollahzadeh, Elnaz, Rodriguez, Sandy, Glackin, Carlotta, Liu, Junjun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904211/
https://ncbi.nlm.nih.gov/pubmed/33626096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247652
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