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Calcium ions trigger the exposure of phosphatidylserine on the surface of necrotic cells

Intracellular Ca(2+) level is under strict regulation through calcium channels and storage pools including the endoplasmic reticulum (ER). Mutations in certain ion channel subunits, which cause mis-regulated Ca(2+) influx, induce the excitotoxic necrosis of neurons. In the nematode Caenorhabditis el...

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Vydáno v:PLoS Genet
Hlavní autoři: Furuta, Yoshitaka, Pena-Ramos, Omar, Li, Zao, Chiao, Lucia, Zhou, Zheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904182/
https://ncbi.nlm.nih.gov/pubmed/33571185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009066
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