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Entinostat improves acute neurological outcomes and attenuates hematoma volume after Intracerebral Hemorrhage

Intracerebral hemorrhage (ICH) or hemorrhagic stroke is a major public health problem with no effective treatment. Given the emerging role of epigenetic mechanisms in the pathophysiology of ICH, we tested the hypothesis that a class 1 histone deacetylase inhibitor (HDACi), Entinostat, attenuates neu...

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Bibliografske podrobnosti
izdano v:Brain Res
Main Authors: Bonsack, Frederick, Sukumari-Ramesh, Sangeetha
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7903810/
https://ncbi.nlm.nih.gov/pubmed/33358731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2020.147222
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