Effect of High-Dose Baclofen on Agitation-Related Events Among Patients With Unhealthy Alcohol Use Receiving Mechanical Ventilation: A Randomized Clinical Trial

IMPORTANCE: Unhealthy alcohol use can lead to agitation in the intensive care unit (ICU). OBJECTIVE: To assess whether high-dose baclofen reduces agitation-related events compared with placebo in patients with unhealthy alcohol use receiving mechanical ventilation. DESIGN, SETTINGS, AND PARTICIPANTS...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Vourc’h, Mickael, Garret, Charlotte, Gacouin, Arnaud, Lacherade, Jean-Claude, Jonas, Maud, Klouche, Kada, Ferrandiere, Martine, Jaber, Samir, Flet, Laurent, Dailly, Eric, Pouplet, Caroline, Maamar, Adel, Reignier, Jean, Roquilly, Antoine, Feuillet, Fanny, Mahe, Pierre-Joachim, Asehnoune, Karim
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2021
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7903253/
https://ncbi.nlm.nih.gov/pubmed/33620407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2021.0658
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