Patients with triple-negative, JAK2V617F- and CALR-mutated essential thrombocythemia share a unique gene expression signature

Approximately 10% to 15% of patients with essential thrombocythemia (ET) lack the common driver mutations, so-called “triple-negative” (TN) disease. We undertook a systematic approach to investigate for somatic mutations and delineate gene expression signatures in 46 TN patients and compared the res...

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Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Alimam, Samah, Villiers, William, Dillon, Richard, Simpson, Michael, Runglall, Manohursingh, Smith, Alexander, Chatzikyriakou, Prodromos, Lavender, Paul, Kanda, Anju, Mills, Ken, Bellosillo Paricio, Beatriz, Kaufman-Cook, James, Ord, Sophie, Kordasti, Shahram, Radia, Deepti, Woodley, Claire, Francis, Yvonne, Mufti, Ghulam, McLornan, Donal P., Harrison, Claire N.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2021
Sujets:
Platelets and Thrombopoiesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7903233/
https://ncbi.nlm.nih.gov/pubmed/33599741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003172
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