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Single-nucleotide methylation specifically represses type I interferon in antiviral innate immunity

Frequent outbreaks of viruses have caused a serious threat to public health. Previous evidence has revealed that DNA methylation is correlated with viral infections, but its role in innate immunity remains poorly investigated. Additionally, DNA methylation inhibitors promote IFN-I by upregulating en...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Gao, Zheng-jun, Li, Wen-ping, Mao, Xin-tao, Huang, Tao, Wang, Hao-li, Li, Yi-ning, Liu, Bao-qin, Zhong, Jiang-yan, Renjie, Chai, Jin, Jin, Li, Yi-yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7903198/
https://ncbi.nlm.nih.gov/pubmed/33616624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201798
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