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Single-nucleotide methylation specifically represses type I interferon in antiviral innate immunity

Frequent outbreaks of viruses have caused a serious threat to public health. Previous evidence has revealed that DNA methylation is correlated with viral infections, but its role in innate immunity remains poorly investigated. Additionally, DNA methylation inhibitors promote IFN-I by upregulating en...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Exp Med
Main Authors: Gao, Zheng-jun, Li, Wen-ping, Mao, Xin-tao, Huang, Tao, Wang, Hao-li, Li, Yi-ning, Liu, Bao-qin, Zhong, Jiang-yan, Renjie, Chai, Jin, Jin, Li, Yi-yuan
פורמט: Artigo
שפה:Inglês
יצא לאור: Rockefeller University Press 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7903198/
https://ncbi.nlm.nih.gov/pubmed/33616624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201798
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