Quantitative Measurement of Cerebrospinal Fluid Amyloid-β Species by Mass Spectrometry

BACKGROUND: High sensitivity liquid chromatography mass spectrometry (LC-MS/MS) was recently introduced to measure amyloid-β (Aβ) species, allowing for a simultaneous assay that is superior to ELISA, which requires more assay steps with multiple antibodies. OBJECTIVE: We validated the Aβ(1-38), Aβ(1...

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Veröffentlicht in:J Alzheimers Dis
Hauptverfasser: Seino, Yusuke, Nakamura, Takumi, Harada, Tomoo, Nakahata, Naoko, Kawarabayashi, Takeshi, Ueda, Tetsuya, Takatama, Masamitsu, Shoji, Mikio
Format: Artigo
Sprache:Inglês
Veröffentlicht: IOS Press 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902963/
https://ncbi.nlm.nih.gov/pubmed/33337370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200987
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