White Matter Hyperintensities Are No Major Confounder for Alzheimer’s Disease Cerebrospinal Fluid Biomarkers

BACKGROUND: The cerebrospinal fluid (CSF) biomarkers amyloid-β 1–42 (Aβ(42)), total and phosphorylated tau (t-tau, p-tau) are increasingly used to assist in the clinical diagnosis of Alzheimer’s disease (AD). However, CSF biomarker levels can be affected by confounding factors. OBJECTIVE: To investi...

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Pubblicato in:J Alzheimers Dis
Autori principali: van Waalwijk van Doorn, Linda J.C., Ghafoorian, Mohsen, van Leijsen, Esther M.C., Claassen, Jurgen A.H.R., Arighi, Andrea, Bozzali, Marco, Cannas, Jorge, Cavedo, Enrica, Eusebi, Paolo, Farotti, Lucia, Fenoglio, Chiara, Fortea, Juan, Frisoni, Giovanni B., Galimberti, Daniela, Greco, Viviana, Herukka, Sanna-Kaisa, Liu, Yawu, Lleó, Alberto, de Mendonça, Alexandre, Nobili, Flavio M., Parnetti, Lucilla, Picco, Agnese, Pikkarainen, Maria, Salvadori, Nicola, Scarpini, Elio, Soininen, Hilkka, Tarducci, Roberto, Urbani, Andrea, Vilaplana, Eduard, Meulenbroek, Olga, Platel, Bram, Verbeek, Marcel M., Kuiperij, H. Bea
Natura: Artigo
Lingua:Inglês
Pubblicazione: IOS Press 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902951/
https://ncbi.nlm.nih.gov/pubmed/33252070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200496
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