Specific residues in the cytoplasmic domain modulate photocurrent kinetics of channelrhodopsin from Klebsormidium nitens

Channelrhodopsins (ChRs) are light-gated ion channels extensively applied as optogenetics tools for manipulating neuronal activity. All currently known ChRs comprise a large cytoplasmic domain, whose function is elusive. Here, we report the cation channel properties of KnChR, one of the photorecepto...

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Udgivet i:Commun Biol
Main Authors: Tashiro, Rintaro, Sushmita, Kumari, Hososhima, Shoko, Sharma, Sunita, Kateriya, Suneel, Kandori, Hideki, Tsunoda, Satoshi P.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902849/
https://ncbi.nlm.nih.gov/pubmed/33623126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01755-5
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