Local computational methods to improve the interpretability and analysis of cryo-EM maps

Cryo-electron microscopy (cryo-EM) maps usually show heterogeneous distributions of B-factors and electron density occupancies and are typically B-factor sharpened to improve their contrast and interpretability at high-resolutions. However, ‘over-sharpening’ due to the application of a single global...

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Udgivet i:Nat Commun
Main Authors: Kaur, Satinder, Gomez-Blanco, Josue, Khalifa, Ahmad A. Z., Adinarayanan, Swathi, Sanchez-Garcia, Ruben, Wrapp, Daniel, McLellan, Jason S., Bui, Khanh Huy, Vargas, Javier
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902670/
https://ncbi.nlm.nih.gov/pubmed/33623015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21509-5
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