Safety and efficacy of combination of suberoylamilide hydroxyamic acid and mitomycin C in reducing pro-fibrotic changes in human corneal epithelial cells

Corneal haze post refractive surgery is prevented by mitomycin c (MMC) treatment though it can lead to corneal endothelial damage, persistent epithelial defects and necrosis of cells. Suberanilohydroxamic acid (SAHA) however has been proposed to prevent corneal haze without any adverse effects. For...

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Publicat a:Sci Rep
Autors principals: Shetty, Rohit, Kumar, Nimisha Rajiv, Subramani, Murali, Krishna, Lekshmi, Murugeswari, Ponnalagu, Matalia, Himanshu, Khamar, Pooja, Dadachanji, Zelda V., Mohan, Rajiv R., Ghosh, Arkasubhra, Das, Debashish
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902619/
https://ncbi.nlm.nih.gov/pubmed/33623133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83881-y
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