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Genomics-directed activation of cryptic natural product pathways deciphers codes for biosynthesis and molecular function

Natural products, which can be isolated from living organisms worldwide, have played a pivotal role in drug discovery since ancient times. However, it has become more challenging to identify a structurally novel molecule with promising biological activity for pharmaceutical development, mainly due t...

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Detalhes bibliográficos
Publicado no:J Nat Med
Autor principal: Tsunematsu, Yuta
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902601/
https://ncbi.nlm.nih.gov/pubmed/33274411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11418-020-01466-x
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