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The extracellular lactate-to-pyruvate ratio modulates the sensitivity to oxidative stress-induced apoptosis via the cytosolic NADH/NAD(+) redox state

The advantages of the Warburg effect on tumor growth and progression are well recognized. However, the relevance of the Warburg effect for the inherent resistance to apoptosis of cancer cells has received much less attention. Here, we show here that the Warburg effect modulates the extracellular lac...

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Bibliografski detalji
Izdano u:Apoptosis
Glavni autori: Go, Simei, Kramer, Thorquil T., Verhoeven, Arthur J., Oude Elferink, Ronald P. J., Chang, Jung-Chin
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902596/
https://ncbi.nlm.nih.gov/pubmed/33230593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-020-01648-8
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