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Siah2 is expressed in adipocyte precursor cells and interacts with EBF1 and ZFP521 to promote adipogenesis
OBJECTIVE: Expression of ZFP423, a key pro-adipogenic transcription factor in adipocyte precursor cells, is regulated by interaction of the pro-adipogenic Early B-cell Factor-1 (EBF1) and anti-adipogenic ZFP521. The ubiquitin ligase Seven-in-absentia homolog 2 (SIAH2) targets ZFP521 for degradation....
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| Publicat a: | Obesity (Silver Spring) |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7902405/ https://ncbi.nlm.nih.gov/pubmed/33155406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.23013 |
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