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Skeletal muscle myosin and cardiac myosin attenuate heparin’s antithrombin-dependent anticoagulant activity

BACKGROUND: Heparin enhances the ability of the plasma protease inhibitor, antithrombin, to neutralize coagulation factor Xa and thrombin. Skeletal muscle myosin binds unfractionated heparin. OBJECTIVES: The aim of this study was to investigate the influence of myosin binding to heparin on antithrom...

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Publicat a:J Thromb Haemost
Autors principals: Morla, Shravan, Deguchi, Hiroshi, Griffin, John H.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902397/
https://ncbi.nlm.nih.gov/pubmed/33176060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.15169
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