Impact of the CYP2C19*17 allele on outcomes in patients receiving genotype-guided antiplatelet therapy after percutaneous coronary intervention

Genotyping for CYP2C19 no function alleles to guide antiplatelet therapy after percutaneous coronary intervention (PCI) improves clinical outcomes. Although results for the increased function CYP2C19*17 allele are also reported, its clinical relevance in this setting remains unclear. A collaboration...

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Publicado no:Clin Pharmacol Ther
Main Authors: Lee, Craig R., Thomas, Cameron D., Beitelshees, Amber L., Tuteja, Sony, Empey, Philip E., Lee, James C., Limdi, Nita A., Duarte, Julio D., Skaar, Todd C., Chen, Yiqing, Cook, Kelsey J., Coons, James C., Dillon, Chrisly, Franchi, Francesco, Giri, Jay, Gong, Yan, Kreutz, Rolf P., McDonough, Caitrin W., Stevenson, James M., Weck, Karen E., Angiolillo, Dominick J., Johnson, Julie A., Stouffer, George A., Cavallari, Larisa H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902344/
https://ncbi.nlm.nih.gov/pubmed/32897581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.2039
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