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Targeting multiple conformations of SARS-CoV2 Papain-Like Protease for drug repositioning: An in-silico study

Papain-Like Protease (PLpro) is a key protein for SARS-CoV-2 viral replication which is the cause of the emerging COVID-19 pandemic. Targeting PLpro can suppress viral replication and provide treatment options for COVID-19. Due to the dynamic nature of its binding site loop, PLpro multiple conformat...

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Detalhes bibliográficos
Publicado no:Comput Biol Med
Main Authors: Ismail, Muhammad I., Ragab, Hanan M., Bekhit, Adnan A., Ibrahim, Tamer M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902231/
https://ncbi.nlm.nih.gov/pubmed/33662683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compbiomed.2021.104295
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