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Dauricine Attenuates Spatial Memory Impairment and Alzheimer-Like Pathologies by Enhancing Mitochondrial Function in a Mouse Model of Alzheimer's Disease

Alzheimer's disease (AD) is characterized by extracellular amyloid plaques composed of β-amyloid (Aβ) and intracellular neurofibrillary tangles containing hyperphosphorylated tau protein. No effective therapy is available for this disease. In this study, we investigated the potential therapeuti...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Chen, Chongyang, Liu, Pan, Wang, Jing, Yu, Haitao, Zhang, Zaijun, Liu, Jianjun, Chen, Xiao, Zhu, Feiqi, Yang, Xifei
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902075/
https://ncbi.nlm.nih.gov/pubmed/33634105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.624339
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