Cytotoxic and Pro-Apoptotic Effects of a Sub-Toxic Concentration of Fluvastatin on OVCAR3 Ovarian Cancer Cells After its Optimized Formulation to Melittin Nano-Conjugates

Fluvastatin (FLV) is a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor often used to lower total and low-density lipoprotein (LDL) cholesterol and for the prevention of adverse cardiovascular events. This drug as well as melittin (MEL), the major component of honeybee venom (Apis mell...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Badr-Eldin, Shaimaa M., Alhakamy, Nabil A., Fahmy, Usama A., Ahmed, Osama A. A., Asfour, Hani Z., Althagafi, Abdulhamid A., Aldawsari, Hibah M., Rizg, Waleed Y., Mahdi, Wael A., Alghaith, Adel F., Alshehri, Sultan, Caraci, Filippo, Caruso, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901935/
https://ncbi.nlm.nih.gov/pubmed/33633571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.642171
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